Endocrine Abstracts

Introduction: Metabolic abnormalities are common in pituitary adenomas and metabolic targeting is becoming a new therapeutic approach to the management of most tumor pathologies, especially pituitary tumors. The objective of this work was to assess the metabolic profile of non-functioning pituitary adenomas.Material and methods: A retrospective and descriptive study, over a period of 6 years, conducted in the Endocrinology-Diabetology and Nutrition depar...

Introduction: Polycystic ovary syndrome is a real public health problem and is the most frequent cause of hyperandrogenism in women of childbearing age. The therapeutic management of PCOS depends on the patient’s phenotype and associated comorbidities. The aim of our work is to study diagnosis and evolution after treatment of PCOS in our population.Material and method: This is a retrospective descriptive study of 78 patients followed for PCOS at the...

Introduction: Papillary thyroid carcinoma is the most common histological type of differentiated thyroid malignancy. This type of tumor is rarely associated with thyroid hormone hypersecretion. We report the case of a patient with papillary thyroid carcinoma revealed by hyperthyroidism. Case report: A 35 years old patient was admitted for the management of malignant hypercalcemia discovered incidentally on the biological workup performed preoperatively f...

Introduction: Growth Hormone deficiency (GHD) is a rare etiology of short stature. The lack of early diagnosis and adequate treatment have adverse consequences, especially the small final height with the resulting psychological impact. The aim of this study is to identify some of the predictive factors influencing stature gain during the first year of GH therapy.Matherials and methods: This is a retrospective and analytical study regarding 36 children wi...

Introduction: Pilomyxoid astrocytoma (PMA) is a rare entity usually described in the hypothalamic-chiasmatic area. It generally concerns infants and very young children. Clinical presentation is not well-defined. But, the therapists should be aware of diencephalic syndrome as an unconventional cause of failure to thrive during early childhood. We report a case of PMA exhibited by failure to thrive;which is a rare outlined association in the litterature.C...

Introduction: Growth hormone deficiency (GHD) is a non-exceptional cause of short stature. Hormonal evaluation and hypothalamic-pituitary MRI are essential to establish the etiological diagnostic. The objective of our study is to assess the different pituitary lesions found in a group of children with GHD.Patients and methods: This is a retrospective longitudinal study of 36 cases of GHD who underwent pituitary MRI examination collected in the Endocrinol...

Introduction: Hypovitaminosis D is prevalent in children with growth hormone deficiency. Infants and young children are special risk groups of vitamin D deficiency due to their rapid growth with high nutritional requirements. The lack of early diagnosis and adequate treatment have adverse outcomes. It impairs particularly bone maturation and increases metabolic risk. The purpose of our study is to assess the vitamin D status of children followed up for GHD in the Endocrinology...

Introduction: Pheochromocytoma is a rare neuroendocrine tumor derived from the adrenal medulla characterized by a high potential of production of catecholamines. The majority of pheochromocytomas are sporadic. However, recent studies show an increasing incidence of hereditary forms.Patients and methods: This is a retrospective descriptive study including 30 patients with pheochromocytoma followed-up in the Endocrinology-Diabetology and Nutrition Departme...

Introduction: Cushing’s disease represents the most frequent etiology of endogenous cushing’s syndrome. It is a severe condition associated to many comorbidities and increased mortality that occurs a long-term management to optimize these patients outcomes. This study aims to describe the phosphocalcium profile and to assess the prevalence of osteporosis in patients with cushing’s disease.Materiels and Methods: Retrospective and descriptiv...

Introduction: Primary hyperparathyroidism (PHP) is a common endocrine disease, and its most effective treatment is surgery. Hungry bone syndrome (HBS) is one of the complications that can occur after parathyroidectomy, and that can cause severe and prolonged hypocalcemia. The aim of this study was to determine the risk factors for HBS in patients who underwent parathyroidectomy for PHP.Patients and Methods: This is a retrospective descriptive and analyti...